bulk solvent造句

• Many of the characteristics of micelles differ from those of bulk solvents.
• This method is useful to prevent artifacts that arise from vacuum simulations and reproduces bulk solvent properties well, but cannot reproduce situations in which individual water molecules have interesting interactions with the molecules under study.
• Their active site is buried in a predominantly hydrophobic cavity at the interface of the alpha / beta-hydrolase core domain and the helical cap domain, and is connected to the bulk solvent by access tunnels.
• Bulk solvent water can then easily deprotonate the lysine side chain, activating it for nucleophilic attack of the SAM cofactor in an S N 2-like reaction resulting in transfer of the methyl group from SAM to the lysine side chain.
• Baker " et al . " we also able to show that acetaldehyde and propionaldehyde are not released into the bulk solvent, but are channeled to an associated acetaldehyde dehydrogenase known as BphJ . This is the first demonstration of substrate channeling in this family of enzymes.
• The connection between the two paths is blocked by the indole ring of Trp234 in the absence of ATP . Water molecules fill the center path in the AMP-PNP and myristoyl-AMP complex structures and through the entrance of the center path, they connect to the bulk solvent regions.
• The free energy of the overall, isolated process of dissolution must be negative for it to occur, where the component free energies contributing include those describing the disintegration of the associations holding the original solute components together, the original associations of the bulk solvent, and the old and new associations between the undissolved and dissolved materials.